OXFORD United regained their second place in the league table with a comprehensive victory 3-0 victory over the Pilgrims at Weston Mill.Argyle's young side found the going hard against their more experienced opponents, and fell behind in the 8th minute.
A few minutes later, the Pilgrims came close to equalising when Emily Mousley finished a nice move down the right and rattled the visitors crossbar with a powerful shot from the right side of the box.
Chloe Bassett following up from the opposite side but was just unable to get a telling touch on the rebound.
With just over 15 minutes on the clock, the Argyle rearguard were caught out by a ball over the top, and the Oxford striker took her chance early, lobbing the advancing Michaela Phillips to double her side's lead.
Although possession was about even, it was the visitors who were more assured on the ball.
Had Argyle been able to exert more sustained pressure they may have got some reward, as the visitors defence did not look to be the strongest.
Argyle's hopes were raised just after half-time when Mousley had her goalbound shot unfairly saved at the foot of the near post by an outfield player resulting in a red card.
Rebekah Rose stepped up to the spot-kick but saw her effort saved.
To rub salt into the home side's wounds, Oxford increased their lead in a counter attacking move with a fine finish into the corner of the net.
Argyle were getting more of the play in the final quarter against the 10 players, but were unable to breach the U’s resolute defending.
With just two games left, Argyle will finish in 3rd place.