Tom Cleverley names an unchanged side from the one that won at Doncaster Rovers last weekend.
Xavier Amaechi comes back into the squad after missing last week's trip to South Yorkshire with a rib injury.
Argyle: 1 Murphy Cooper, 5 Julio Pleguezuelo, 7 Harvey White, 9 Will Evans, 11 Ronan Curtis, 14 Oliver Irow, 15 Alex Mitchell, 19 Tyreeq Bakinson, 27 Bim Pepple, 29 Matty Sorinola, 45 Wes Harding (capt). Substitutes: 21 James Storer (GK), 2 Mathias Ross, 8 Joe Edwards, 10 Xavier Amaechi, 17 Caleb Watts, 18 Owen Oseni, 23 Bradley Ibrahim.
Barnsley: 25 Rogan Ravenhill, 2 Arley Kay, 4 Sam Gale, 6 Connor O'Riordan, 8 Cameron McGeehan (capt), 9 Makenzie Kirk, 11 Tyrese Noslin, 19 Reyes Cleary, 22 Patrick Kelly, 30 Jonathan Bland, 36 Luke Alker. Substitutes: 51 Kieran Flavell (GK), 5 Jack Shepherd, 10 Ben Hamed Toure, 13 Clayton Taylor, 17 Amani Richards, 39 Leo Farrell, 48 Luca Connell.
