Tom Cleverley makes five changes to the side that beat Alvechurch in the Emirates FA Cup last weekend.
Murphy Cooper makes his return in goal, replacing James Storer. In defence, Jack MacKenzie and Alex Hartridge come in for Joe Edwards and Alex Mitchell. Ronan Curtis is preferred to Oliver Irow and Bradley Ibrahim is in for the injured Bim Pepple.
Sheffield Wednesday: 1 Joe Lumley, 5 Di'Shon Bernard, 6 Liam Cooper, 7 Yan Valery, 8 Callum Slattery, 9 Jamal Lowe, 10 Barry Bannan (capt), 16 Billy Mitchell, 18 Jaden Heskey, 26 Sil Swinkels, 50 Davis Keillor-Dunn. Substitutes: 27 Connal Trueman (gk), 2 Liam Palmer, 4 Ricardo Santos, 11 Louie Barry, 24 Harry Gray, 30 Ernie Weaver, 37 Jarvis Thornton.
Argyle: 1 Murphy Cooper, 2 Mathias Ross, 3 Jack MacKenzie, 6 Malachi Boateng, 7 Harvey White, 9 Will Evans, 10 Xavier Amaechi, 11 Ronan Curtis, 22 Alex Hartridge, 23 Bradley Ibrahim, 45 Wes Harding (capt). Substitutes: 21 James Storer (GK), 14 OIiver Irow, 17 Caleb Watts, 18 Owen Oseni, 38 Seb Campbell, 40 Joe Mwaro, 46 Frankie Maund.
